Across TCGA patient cohorts, RIPPLY3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,669 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RIPPLY3-associated proteins across cancer lineages are SMC1A, FN3K, and MAGED2. Each is linked with RIPPLY3 in more than 4 cancer types. Because this analysis shows association rather than direction, both RIPPLY3-to-partner and partner-to-RIPPLY3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPPLY3→partner) and Y-score (partner→RIPPLY3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SMC1A →	+0.242	+0.651	<.001	.004	3	5
HNSC	FN3K →	+0.529	+1.014	<.001	<.001	3	4
LSCC	MAGED2 →	+0.465	+0.851	<.001	.001	3	4
LUAD	TOP2A →	+0.839	+0.807	<.001	<.001	3	4
LUAD	TOP2A_S1374 →	+1.613	+1.196	<.001	.001	3	4
OV	TPX2 →	+0.676	+0.848	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,669 associations by consensus.

Exploration

RIPPLY3 survival (RNA) · tumor vs normal (RNA) · all RIPPLY3 data types