RIPOR3-AS1

Across TCGA pan-cancer cohorts, RIPOR3-AS1 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RIPOR3-AS1 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher RIPOR3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RIPOR3-AS1 expression acts as an unfavorable survival marker, although some lineages such as COAD and ACC show a favorable association.

DLBC, COAD, and UVM are the cancer types where RIPOR3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	All	0.403	0.931	<.001	63	view →
COAD	DFS	Quartile	All	0.909	0.733	.001	41	view →
UVM	DFS	Tertile	All	0.278	0.598	.009	36	view →
ACC	DFS	Tertile	All	0.844	0.424	.003	23	view →
CHOL	OS	Tertile	II,III,IV	0.024	0.601	.025	18	view →
THYM	DFS	Quartile	III,IV	0.310	0.895	.005	13	view →
OV	OS	Quartile	All	0.757	0.880	.011	12	view →
SKCM	OS	Tertile	IV	0.156	0.560	.040	9	view →
THCA	OS	Quartile	II,III,IV	0.882	0.984	.010	9	view →
LUSC	DFS	Quartile	All	0.707	0.322	.003	8	view →
MESO	DFS	Median	All	0.474	0.338	.044	8	view →
SARC	OS	Quartile	All	0.880	0.673	.012	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RIPOR3-AS1–DLBC (DFS)

Open the DLBC breakdown →