RIPOR3-AS1

Across TCGA pan-cancer cohorts, RIPOR3-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of RIPOR3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RIPOR3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RIPOR3-AS1 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

BRCA, KIRC, and LUAD are the cancer types where RIPOR3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RIPOR3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	+0.210	<.001	6	view →
KIRC	Male	II,III,IV	−0.148	<.001	6	view →
LUAD	All	IV	+0.345	.040	3	view →
KIRP	Male	All	−0.133	.025	2	view →
LUSC	All	All	+0.053	.041	2	view →
BLCA	All	IV	+0.864	.049	1	view →
COAD	Female	III,IV	+0.184	.025	1	view →
LIHC	Female	All	+0.026	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

RIPOR3-AS1–BRCA

Open the BRCA breakdown →