RIPOR2

Across TCGA cell cohorts, RIPOR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,400 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RIPOR2-associated GO terms across cancer lineages are Regulation of protein localization to cell leading edge, Regulation of cell cycle G1/S phase transition, and Regulation of translational initiation. Each is linked with RIPOR2 in more than 16 cancer types. Because this analysis shows association rather than direction, both RIPOR2-to-partner and partner-to-RIPOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to cell leading edge grouped by RIPOR2-low versus RIPOR2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIPOR2→partner) and Y-score (partner→RIPOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of protein localization to cell leading edge →	-0.241	-2.457	<.001	<.001	3	17
BLOOD_Leukemia	Regulation of cell cycle G1/S phase transition →	+0.044	+1.680	<.001	<.001	3	9
LARGE_INTESTINE	Regulation of translational initiation →	+0.066	+0.411	<.001	.005	3	8
SOFT_TISSUE	Negative regulation of binding of sperm to zona pellucida →	-1.423	-2.332	<.001	<.001	3	7
SOFT_TISSUE	Regulation of acrosomal vesicle exocytosis →	-0.733	-2.563	<.001	<.001	3	7
OVARY	Regulation of cytoplasmic translation →	+0.115	+1.158	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,400 associations by consensus.

Regulation of protein localization to cell leading edge by RIPOR2 expression — SOFT_TISSUE

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