RIN2

Across TCGA cell cohorts, RIN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,615 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RIN2-associated GO terms across cancer lineages are Positive regulation of protein localization to plasma membrane, Regulation of plasma membrane repair, and Regulation of cell-substrate adhesion. Each is linked with RIN2 in more than 13 cancer types. Because this analysis shows association rather than direction, both RIN2-to-partner and partner-to-RIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to plasma membrane grouped by RIN2-low versus RIN2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIN2→partner) and Y-score (partner→RIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of protein localization to plasma membrane →	+0.119	+1.696	<.001	<.001	3	14
BONE	Regulation of plasma membrane repair →	+0.370	+1.641	<.001	<.001	3	14
BONE	Regulation of cell-substrate adhesion →	+0.157	+1.860	<.001	<.001	3	13
BONE	Regulation of actin filament organization →	+0.077	+1.550	<.001	<.001	3	13
BONE	Vesicle-mediated transport to the plasma membrane →	+0.074	+1.648	<.001	<.001	2	13
BONE	Positive regulation of cell-substrate adhesion →	+0.171	+1.832	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,615 associations by consensus.

Positive regulation of protein localization to plasma membrane by RIN2 expression — BONE

Explore this box plot interactively →