RIN1

Across TCGA patient cohorts, RIN1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,600 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RIN1-associated genes across cancer lineages are FOSL1, PTPRH, and ITGA3. Each is linked with RIN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both RIN1-to-partner and partner-to-RIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIN1 versus FOSL1 in LUAD, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIN1→partner) and Y-score (partner→RIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	FOSL1 →	+1.189	+0.418	<.001	<.001	3	7
CCRCC	PTPRH →	+1.495	+0.420	<.001	.002	3	6
HNSC	ITGA3 →	+0.962	+0.538	<.001	<.001	3	5
HNSC	SP4 →	-0.565	-0.464	.002	.001	3	5
HNSC	IRAK1BP1 →	-0.535	-0.343	<.001	<.001	3	5
HNSC	ANKRD23 →	-0.534	-0.711	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,600 associations by consensus.

RIN1 vs FOSL1 — LUAD

Explore this scatter interactively →