RIMS3

Across TCGA cell cohorts, RIMS3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,437 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RIMS3-associated GO terms across cancer lineages are Positive regulation of DNA repair, Positive regulation of double-strand break repair, and Regulation of DNA repair. Each is linked with RIMS3 in more than 13 cancer types. Because this analysis shows association rather than direction, both RIMS3-to-partner and partner-to-RIMS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by RIMS3-low versus RIMS3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMS3→partner) and Y-score (partner→RIMS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of DNA repair →	+0.073	+1.553	<.001	<.001	3	14
STOMACH	Positive regulation of double-strand break repair →	+0.076	+1.017	.003	.006	3	13
BONE	Regulation of DNA repair →	+0.085	+1.628	.002	.001	3	13
STOMACH	Regulation of nucleotide-excision repair →	+0.142	+1.299	.003	.002	3	12
BONE	Epigenetic regulation of gene expression →	+0.098	+1.656	<.001	.001	2	13
BONE	Positive regulation of DNA metabolic process →	+0.104	+1.828	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,437 associations by consensus.

Positive regulation of DNA repair by RIMS3 expression — BONE

Explore this box plot interactively →