RIMS3

Across TCGA cell cohorts, RIMS3 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RIMS3-associated genes across cancer lineages are AVP, GML, and OR56A4. Each is linked with RIMS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIMS3-to-partner and partner-to-RIMS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by RIMS3-low versus RIMS3-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMS3→partner) and Y-score (partner→RIMS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
BLOOD_Leukemia	GML →	+0.088	+4.152	<.001	.009	3	1
BLOOD_Leukemia	OR56A4 →	+0.011	+4.874	<.001	.002	3	1
BLOOD_Leukemia	TSSK1B →	+0.014	+4.874	<.001	.002	3	1
BLOOD_Leukemia	MTRNR2L6 →	+0.101	+5.269	<.001	<.001	3	1
LUNG_NSCLC_LUAD	OR12D3 →	+0.025	+5.228	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

AVP by RIMS3 expression — BLOOD_Lymphoma

Explore this box plot interactively →