RIMKLA

Across TCGA patient cohorts, RIMKLA protein abundance is significantly associated with the RNA expression of many other genes, with 431 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RIMKLA-associated genes across cancer lineages are RHBDL1, STAB1, and ELOB. Each is linked with RIMKLA in more than 1 cancer types. Because this analysis shows association rather than direction, both RIMKLA-to-partner and partner-to-RIMKLA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RIMKLA versus RHBDL1 in CCRCC, with a Pearson correlation of -0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMKLA→partner) and Y-score (partner→RIMKLA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	RHBDL1 →	-1.136	-0.934	<.001	.008	3	1
CCRCC	STAB1 →	+1.068	+0.934	.001	.008	3	1
CCRCC	ELOB →	-0.398	-0.934	<.001	.008	3	1
CCRCC	LILRB5 →	+1.370	+0.934	<.001	.008	3	1
CCRCC	MYH15 →	-0.947	-1.327	.002	.008	3	1
CCRCC	PLIN2 →	-1.483	-0.934	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 431 associations by consensus.

RIMKLA vs RHBDL1 — CCRCC

Explore this scatter interactively →