RIMBP3

Across TCGA patient cohorts, RIMBP3 mutation is significantly associated with the immune_cell of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RIMBP3-associated genes across cancer lineages are Erythrocytes, Mesangial cells, and mv Endothelial cells. Each is linked with RIMBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIMBP3-to-partner and partner-to-RIMBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by RIMBP3-low versus RIMBP3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMBP3→partner) and Y-score (partner→RIMBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Erythrocytes →	+0.026	+2.321	.039	.036	3	1
UCEC	Mesangial cells →	-0.047	-2.311	.014	.036	3	1
UCEC	mv Endothelial cells →	-0.031	-2.311	.008	.036	3	1
UCEC	lymphatic Endothelial cells →	-0.028	-3.405	.017	.005	2	1
UCEC	Mast cells →	+0.021	+3.502	.008	.002	2	1
UCEC	Endothelial cells →	-0.050	-3.416	.009	.005	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Erythrocytes by RIMBP3 expression — UCEC

Explore this box plot interactively →