RIMBP3

Across TCGA cell cohorts, RIMBP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,464 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RIMBP3-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Mitotic cytokinesis. Each is linked with RIMBP3 in more than 12 cancer types. Because this analysis shows association rather than direction, both RIMBP3-to-partner and partner-to-RIMBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by RIMBP3-low versus RIMBP3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMBP3→partner) and Y-score (partner→RIMBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Symbiont-mediated disruption of host cellular anatomical structure →	+0.113	+0.214	.008	.008	3	13
URINARY_TRACT	Symbiont-mediated disruption of host anatomical structure →	+0.113	+0.214	.008	.008	3	13
UPPER_AERODIGESTIVE_TRACT	Mitotic cytokinesis →	+0.064	+0.215	.007	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.125	+0.280	<.001	<.001	3	10
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.128	+0.393	.005	.003	3	10
BREAST	Positive regulation of DNA-templated transcription initiation →	+0.062	+0.350	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,464 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by RIMBP3 expression — URINARY_TRACT

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