RIMBP3

Across TCGA cell cohorts, RIMBP3 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RIMBP3-associated genes across cancer lineages are KRT37, COX6A2, and OR1L6. Each is linked with RIMBP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIMBP3-to-partner and partner-to-RIMBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT37 grouped by RIMBP3-low versus RIMBP3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIMBP3→partner) and Y-score (partner→RIMBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	KRT37 →	+0.015	+5.569	<.001	.001	3	1
LARGE_INTESTINE	COX6A2 →	+0.068	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR1L6 →	+0.018	+4.022	<.001	.006	3	1
LARGE_INTESTINE	FMR1NB →	+0.209	+3.453	<.001	.009	3	1
LARGE_INTESTINE	OR2T33 →	+0.134	+3.453	.003	.009	3	1
LARGE_INTESTINE	FAM187B →	+0.020	+3.347	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

KRT37 by RIMBP3 expression — BLOOD_Leukemia

Explore this box plot interactively →