RIIAD1

Across TCGA patient cohorts, RIIAD1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RIIAD1-associated genes across cancer lineages are SPCS2P2, LINC02563, and MIR4743. Each is linked with RIIAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIIAD1-to-partner and partner-to-RIIAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPCS2P2 grouped by RIIAD1-low versus RIIAD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIIAD1→partner) and Y-score (partner→RIIAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPCS2P2 →	+0.078	+3.198	.002	.009	3	1
UCEC	LINC02563 →	+0.226	+3.683	<.001	.003	3	1
UCEC	MIR4743 →	+0.188	+4.660	<.001	.003	3	1
UCEC	OR4K8P →	+0.041	+4.660	<.001	.003	3	1
UCEC	NPB →	+0.078	+4.082	.005	.001	3	1
UCEC	RNU1-17P →	+0.361	+3.198	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

SPCS2P2 by RIIAD1 expression — UCEC

Explore this box plot interactively →