RICTOR

Across TCGA patient cohorts, RICTOR protein abundance is significantly associated with the RNA expression of many other genes, with 9,668 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RICTOR-associated genes across cancer lineages are CXCL5, NIPBL, and BRIX1. Each is linked with RICTOR in more than 4 cancer types. Because this analysis shows association rather than direction, both RICTOR-to-partner and partner-to-RICTOR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RICTOR versus CXCL5 in PDAC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RICTOR→partner) and Y-score (partner→RICTOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CXCL5 →	+1.793	+0.132	<.001	.003	3	5
LSCC	NIPBL →	+0.588	+0.188	<.001	<.001	3	5
HNSC	BRIX1 →	+0.781	+0.260	<.001	<.001	3	5
HNSC	C5orf22 →	+0.655	+0.230	.001	<.001	3	5
CCRCC	GFPT2 →	+1.000	+0.069	.004	.006	3	4
COAD	NOC2L →	+0.369	+0.208	.004	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,668 associations by consensus.

RICTOR vs CXCL5 — PDAC

Explore this scatter interactively →