RIC3-DT

Across TCGA pan-cancer cohorts, RIC3-DT RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated RIC3-DT data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RIC3-DT RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RIC3-DT expression acts as an unfavorable survival marker, although some lineages such as UCS and LUAD show a favorable association.

UCS, MESO, and LUAD are the cancer types where RIC3-DT RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	II,III,IV	0.632	0.230	.005	28	view →
MESO	OS	Tertile	II,III,IV	0.239	0.636	.007	27	view →
LUAD	DFS	Tertile	III,IV	0.869	0.608	.020	24	view →
PCPG	OS	Tertile	All	0.346	1.000	.006	22	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	18	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
KIRC	DFS	Tertile	II,III,IV	0.334	0.548	.024	14	view →
LUSC	DFS	Tertile	III,IV	0.137	0.707	.020	9	view →
LGG	OS	Median	All	0.743	0.892	.004	6	view →
ACC	DFS	Tertile	IV	0.731	0.239	.035	6	view →
UCEC	DFS	Tertile	All	0.460	0.688	.030	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

RIC3-DT–UCS (DFS)

Open the UCS breakdown →