RIBC2

Across TCGA patient cohorts, RIBC2 mutation is significantly associated with the RNA expression of many other genes, with 502 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RIBC2-associated genes across cancer lineages are MIR7976, RNU4-79P, and RNA5SP142. Each is linked with RIBC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RIBC2-to-partner and partner-to-RIBC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7976 grouped by RIBC2-low versus RIBC2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RIBC2→partner) and Y-score (partner→RIBC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR7976 →	+0.477	+2.968	<.001	.001	3	2
LGG	RNU4-79P →	+0.298	+7.977	<.001	.007	3	1
LGG	RNA5SP142 →	+0.338	+7.977	<.001	.007	3	1
LGG	RN7SKP286 →	+0.159	+7.977	<.001	.007	3	1
LGG	TTTY20 →	+0.179	+7.977	<.001	.007	3	1
LGG	USP9YP10 →	+0.049	+7.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 502 associations by consensus.

MIR7976 by RIBC2 expression — UCEC

Explore this box plot interactively →