Across TCGA cell cohorts, RHOXF2B mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RHOXF2B-associated genes across cancer lineages are OTUD6A, SPAG11A, and ACSM2A. Each is linked with RHOXF2B in more than 1 cancer types. Because this analysis shows association rather than direction, both RHOXF2B-to-partner and partner-to-RHOXF2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOXF2B→partner) and Y-score (partner→RHOXF2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OTUD6A →	+0.113	+5.209	<.001	.005	3	2
BLOOD_Myeloma	SPAG11A →	+0.049	+4.807	<.001	.006	3	1
BLOOD_Myeloma	ACSM2A →	+0.016	+4.807	<.001	.006	3	1
BLOOD_Lymphoma	PPP1R2C →	+0.456	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	TAS2R7 →	+0.042	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	FTHL17 →	+0.239	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

RHOXF2B survival (RNA) · tumor vs normal (RNA) · all RHOXF2B data types