RHOXF2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RHOXF2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHOXF2-associated genes across cancer lineages are Endothelial cells, lymphatic Endothelial cells, and pDC. Each is linked with RHOXF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHOXF2-to-partner and partner-to-RHOXF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by RHOXF2-low versus RHOXF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOXF2→partner) and Y-score (partner→RHOXF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEndothelial cells →-0.040-2.657.020.00631
UCEClymphatic Endothelial cells →-0.023-2.968.032.03631
UCECpDC →+0.045+3.032.039.01831
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Endothelial cells by RHOXF2 expression — UCEC

Box plot of Endothelial cells in RHOXF2-low vs RHOXF2-high samples in UCEC.

Explore this box plot interactively →

Exploration