RHOXF2

Across TCGA pan-cancer cohorts, RHOXF2 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RHOXF2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RHOXF2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RHOXF2 is over-expressed in tumor.

KICH, BLCA, and KIRP are the cancer types where RHOXF2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RHOXF2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	+0.544	<.001	5	view →
BLCA	All	III,IV	+0.025	.027	3	view →
KIRP	Female	II,III,IV	+0.032	.041	2	view →
LIHC	All	All	+0.166	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RHOXF2–KICH

Open the KICH breakdown →