RHOQ

Across TCGA patient cohorts, RHOQ protein abundance is significantly associated with the RNA expression of many other genes, with 5,703 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RHOQ-associated genes across cancer lineages are DNTTIP1, E2F3, and PEX5L. Each is linked with RHOQ in more than 2 cancer types. Because this analysis shows association rather than direction, both RHOQ-to-partner and partner-to-RHOQ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHOQ versus DNTTIP1 in CCRCC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOQ→partner) and Y-score (partner→RHOQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	DNTTIP1 →	+0.442	+0.256	.001	.001	3	2
OV	E2F3 →	+0.539	+0.414	.002	.001	3	2
GBM	PEX5L →	+1.491	+0.397	<.001	.004	3	2
OV	FABP6 →	+1.688	+0.424	.004	.003	3	2
OV	SLC35F3 →	+1.361	+0.458	<.001	<.001	3	2
UCEC	RABGAP1 →	-0.561	-0.673	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,703 associations by consensus.

RHOQ vs DNTTIP1 — CCRCC

Explore this scatter interactively →