RHOH

Across TCGA cell cohorts, RHOH RNA expression is significantly associated with the go_rna of many other GO terms, with 5,380 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RHOH-associated GO terms across cancer lineages are Heterotypic cell-cell adhesion, DNA conformation change, and Chromosomal 5-methylcytosine DNA demethylation pathway. Each is linked with RHOH in more than 6 cancer types. Because this analysis shows association rather than direction, both RHOH-to-partner and partner-to-RHOH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterotypic cell-cell adhesion grouped by RHOH-low versus RHOH-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOH→partner) and Y-score (partner→RHOH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Heterotypic cell-cell adhesion →	-0.169	-3.030	<.001	<.001	3	7
BONE	DNA conformation change →	+0.132	+3.634	<.001	<.001	3	7
BREAST	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.100	+1.313	<.001	<.001	3	7
BLOOD_Leukemia	Regulation of transcription initiation by RNA polymerase II →	+0.046	+1.690	<.001	<.001	3	6
BONE	Regulation of acrosome reaction →	+1.410	+4.039	<.001	<.001	3	6
SKIN	Optic nerve development →	-0.222	-0.105	<.001	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,380 associations by consensus.

Heterotypic cell-cell adhesion by RHOH expression — BONE

Explore this box plot interactively →