RHOBTB3

Across TCGA patient cohorts, RHOBTB3 mutation is significantly associated with the RNA expression of many other genes, with 2,464 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHOBTB3-associated genes across cancer lineages are RBMY2KP, RNU1-31P, and RNA5SP138. Each is linked with RHOBTB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHOBTB3-to-partner and partner-to-RHOBTB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY2KP grouped by RHOBTB3-low versus RHOBTB3-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOBTB3→partner) and Y-score (partner→RHOBTB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RBMY2KP →	+0.064	+8.055	<.001	.007	3	2
SKCM	RNU1-31P →	+0.169	+4.513	<.001	.009	3	2
UCEC	RNA5SP138 →	+0.272	+2.699	<.001	.003	3	2
UCEC	CNN2P10 →	+0.084	+1.415	.009	.008	3	2
UCEC	LINC01400 →	+0.072	+1.670	<.001	.006	3	2
UCEC	CDC42P2 →	+0.143	+1.459	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,464 associations by consensus.

RBMY2KP by RHOBTB3 expression — BRCA

Explore this box plot interactively →