RHOBTB3

Across TCGA cell cohorts, RHOBTB3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,443 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible RHOBTB3-associated GO terms across cancer lineages are Maintenance of protein location, Negative regulation of protein catabolic process, and Viral process. Each is linked with RHOBTB3 in more than 12 cancer types. Because this analysis shows association rather than direction, both RHOBTB3-to-partner and partner-to-RHOBTB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of protein location grouped by RHOBTB3-low versus RHOBTB3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOBTB3→partner) and Y-score (partner→RHOBTB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Maintenance of protein location →	+0.135	+2.219	.006	.003	3	13
STOMACH	Negative regulation of protein catabolic process →	+0.115	+3.654	<.001	<.001	3	12
BONE	Viral process →	+0.092	+1.396	.002	.001	3	12
BONE	Regulation of focal adhesion assembly →	+0.181	+1.420	<.001	<.001	3	12
BONE	Regulation of cell-substrate junction assembly →	+0.181	+1.420	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Regulation of fibroblast proliferation →	+0.097	+2.514	.002	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,443 associations by consensus.

Maintenance of protein location by RHOBTB3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →