RHOBTB1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RHOBTB1 protein abundance is significantly associated with the RNA expression of many other genes, with 656 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHOBTB1-associated genes across cancer lineages are DHRS7, MYBL2, and PHKB. Each is linked with RHOBTB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHOBTB1-to-partner and partner-to-RHOBTB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHOBTB1 versus DHRS7 in LUAD, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOBTB1→partner) and Y-score (partner→RHOBTB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADDHRS7 →+0.634+0.435<.001<.00131
LUADMYBL2 →-2.199-0.531.007.00731
LUADPHKB →+0.525+0.423<.001<.00131
LUADHOXA6 →-1.094-0.520.002<.00131
LUADC5 →+1.456+0.405<.001.00531
LUADTYRP1 →+1.587+0.537.007<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 656 associations by consensus.

RHOBTB1 vs DHRS7 — LUAD

Per-sample scatter of RHOBTB1 vs DHRS7 in LUAD (Pearson r = 0.52).

Explore this scatter interactively →

Exploration