RHOA

Across TCGA patient cohorts, RHOA RNA expression is significantly associated with the protein abundance of many other proteins, with 16,011 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RHOA-associated proteins across cancer lineages are RCN3, LUZP1, and MAP4. Each is linked with RHOA in more than 5 cancer types. Because this analysis shows association rather than direction, both RHOA-to-partner and partner-to-RHOA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHOA versus RCN3 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RHOA→partner) and Y-score (partner→RHOA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RCN3 →	+0.551	+0.495	.002	<.001	3	6
GBM	LUZP1 →	+0.353	+0.291	<.001	<.001	3	6
OV	MAP4 →	+0.312	+0.517	.002	.001	3	5
OV	TLN1 →	+0.344	+0.436	<.001	.001	3	5
CCRCC	PALLD_S772 →	+0.718	+0.252	.001	.008	3	5
BRCA	PDCD6IP →	+0.320	+0.445	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,011 associations by consensus.

RHOA vs RCN3 — OV

Explore this scatter interactively →