RHO

Across TCGA patient cohorts, RHO RNA expression is significantly associated with the go_rna of many other GO terms, with 7,054 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RHO-associated GO terms across cancer lineages are Protein stabilization, Protein polymerization, and Obsolete histone H3-K4 methylation. Each is linked with RHO in more than 23 cancer types. Because this analysis shows association rather than direction, both RHO-to-partner and partner-to-RHO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein stabilization grouped by RHO-low versus RHO-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHO→partner) and Y-score (partner→RHO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein stabilization →	+0.062	+0.058	<.001	<.001	3	24
ESCA	Protein polymerization →	+0.074	+0.136	<.001	<.001	3	22
SCLC	Obsolete histone H3-K4 methylation →	+0.135	+0.177	<.001	.003	2	23
ESCA	Regulation of microtubule cytoskeleton organization →	+0.076	+0.097	<.001	<.001	3	22
ESCA	Regulation of transcription elongation by RNA polymerase II →	+0.073	+0.151	<.001	<.001	3	22
SCLC	Positive regulation of double-strand break repair →	+0.092	+0.132	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,054 associations by consensus.

Protein stabilization by RHO expression — STAD

Explore this box plot interactively →