RHNO1

Across TCGA cell cohorts, RHNO1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,438 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RHNO1-associated GO terms across cancer lineages are Spindle elongation, Metaphase chromosome alignment, and Regulation of chromosome segregation. Each is linked with RHNO1 in more than 16 cancer types. Because this analysis shows association rather than direction, both RHNO1-to-partner and partner-to-RHNO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle elongation grouped by RHNO1-low versus RHNO1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHNO1→partner) and Y-score (partner→RHNO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Spindle elongation →	+0.251	+0.736	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Metaphase chromosome alignment →	+0.125	+1.176	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome segregation →	+0.132	+1.010	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle G2/M phase transition →	+0.114	+1.004	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cell cycle →	+0.084	+1.174	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of metaphase/anaphase transition of cell cycle →	+0.132	+1.104	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,438 associations by consensus.

Spindle elongation by RHNO1 expression — SOFT_TISSUE

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