RHNO1

Across TCGA cell cohorts, RHNO1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RHNO1-associated genes across cancer lineages are NPHS2, CDX4, and OR5C1. Each is linked with RHNO1 in more than 1 cancer types. Because this analysis shows association rather than direction, both RHNO1-to-partner and partner-to-RHNO1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPHS2 grouped by RHNO1-low versus RHNO1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHNO1→partner) and Y-score (partner→RHNO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NPHS2 →	+0.108	+4.029	<.001	.009	3	1
LARGE_INTESTINE	CDX4 →	+0.011	+4.217	<.001	.001	3	1
LARGE_INTESTINE	OR5C1 →	+0.038	+3.793	.002	.007	3	1
LARGE_INTESTINE	KRTAP12-3 →	+0.052	+4.437	<.001	.004	3	1
LARGE_INTESTINE	PPEF2 →	+0.045	+3.736	<.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

NPHS2 by RHNO1 expression — LARGE_INTESTINE

Explore this box plot interactively →