RHEX

Across TCGA cell cohorts, RHEX RNA expression is significantly associated with the go_rna of many other GO terms, with 2,345 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible RHEX-associated GO terms across cancer lineages are Purine ribonucleotide metabolic process, Ribonucleoside triphosphate biosynthetic process, and Regulation of intracellular protein transport. Each is linked with RHEX in more than 4 cancer types. Because this analysis shows association rather than direction, both RHEX-to-partner and partner-to-RHEX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine ribonucleotide metabolic process grouped by RHEX-low versus RHEX-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHEX→partner) and Y-score (partner→RHEX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Purine ribonucleotide metabolic process →	+0.069	+2.672	<.001	<.001	3	5
BONE	Ribonucleoside triphosphate biosynthetic process →	+0.083	+0.023	.002	.006	3	5
CNS	Regulation of intracellular protein transport →	+0.039	+0.024	<.001	.003	3	5
CNS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.051	+0.032	.004	<.001	3	5
OVARY	Regulation of biomineral tissue development →	-0.050	-2.342	<.001	<.001	3	4
OVARY	Protein localization to mitochondrion →	+0.086	+2.979	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,345 associations by consensus.

Purine ribonucleotide metabolic process by RHEX expression — OVARY

Explore this box plot interactively →