RHEX

Across TCGA cell cohorts, RHEX protein abundance is significantly associated with the RNA expression of many other genes, with 1,612 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible RHEX-associated genes across cancer lineages are CYP2U1, DCAF16, and NOP14. Each is linked with RHEX in more than 4 cancer types. Because this analysis shows association rather than direction, both RHEX-to-partner and partner-to-RHEX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHEX versus CYP2U1 in URINARY_TRACT, with a Pearson correlation of -0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHEX→partner) and Y-score (partner→RHEX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CYP2U1 →	-0.964	-0.897	.006	.002	3	5
LUNG_NSCLC_LUAD	DCAF16 →	+0.703	+0.578	.002	<.001	3	5
OVARY	NOP14 →	+0.925	+1.050	.003	.005	3	4
CNS	CENPH →	+0.763	+0.796	.004	.003	3	4
LUNG_NSCLC_LUAD	TACC3 →	+0.945	+1.007	<.001	<.001	3	4
KIDNEY	RPL13 →	+0.730	+0.728	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,612 associations by consensus.

RHEX vs CYP2U1 — URINARY_TRACT

Explore this scatter interactively →