Across TCGA patient cohorts, RHCE mutation is significantly associated with the RNA expression of many other genes, with 596 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHCE-associated genes across cancer lineages are CXCL10, NDUFA5P5, and RNU6-542P. Each is linked with RHCE in more than 2 cancer types. Because this analysis shows association rather than direction, both RHCE-to-partner and partner-to-RHCE results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHCE→partner) and Y-score (partner→RHCE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CXCL10 →	+1.000	+2.606	.009	.005	3	3
CESC	NDUFA5P5 →	+0.112	+7.584	<.001	<.001	3	2
CESC	RNU6-542P →	+0.313	+5.539	<.001	.004	3	2
CESC	DNM1P5 →	+0.087	+6.569	<.001	.001	3	2
UCEC	GBP5 →	+0.843	+2.081	.002	.001	3	2
UCEC	CXCL13 →	+1.725	+2.736	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 596 associations by consensus.

Exploration

RHCE survival (RNA) · tumor vs normal (RNA) · all RHCE data types