RHBG

Across TCGA patient cohorts, RHBG protein abundance is significantly associated with the RNA expression of many other genes, with 784 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RHBG-associated genes across cancer lineages are SOX10, NEFH, and PNPLA5. Each is linked with RHBG in more than 1 cancer types. Because this analysis shows association rather than direction, both RHBG-to-partner and partner-to-RHBG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RHBG versus SOX10 in GBM, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBG→partner) and Y-score (partner→RHBG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SOX10 →	+2.668	+1.189	<.001	<.001	3	1
GBM	NEFH →	+1.810	+1.195	<.001	<.001	3	1
GBM	PNPLA5 →	+0.488	+1.543	<.001	<.001	3	1
GBM	CHGA →	+2.887	+1.411	<.001	<.001	3	1
GBM	ITPK1 →	+1.047	+1.242	<.001	.001	3	1
GBM	CPNE6 →	+1.798	+1.227	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 784 associations by consensus.

RHBG vs SOX10 — GBM

Explore this scatter interactively →