RHBG

Across TCGA pan-cancer cohorts, RHBG RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated RHBG data layer compared with 6 for mutation status.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher RHBG RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RHBG expression acts as an unfavorable survival marker, although some lineages such as BLCA and KICH show a favorable association.

KIRP, KIRC, and ACC are the cancer types where RHBG RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	All	0.320	0.693	<.001	81	view →
KIRC	OS	Tertile	All	0.772	0.867	<.001	74	view →
ACC	DFS	Quartile	All	0.245	0.764	<.001	55	view →
LGG	DFS	Tertile	All	0.662	0.838	<.001	48	view →
BLCA	OS	Median	II,III,IV	0.566	0.336	<.001	42	view →
DLBC	DFS	Median	IV	0.136	0.817	.002	42	view →
KICH	OS	Tertile	III,IV	0.819	0.233	.004	34	view →
MESO	OS	Tertile	All	0.300	0.481	.010	30	view →
SKCM	DFS	Median	All	0.672	0.824	<.001	24	view →
UVM	DFS	Tertile	III,IV	0.801	0.331	.002	21	view →
ESCA	OS	Median	III,IV	0.695	0.421	.002	21	view →
CHOL	DFS	Tertile	II,III,IV	0.157	0.629	.003	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

RHBG–KIRP (DFS)

Open the KIRP breakdown →