RHBG

Across TCGA patient cohorts, RHBG mutation is significantly associated with the RNA expression of many other genes, with 946 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHBG-associated genes across cancer lineages are MEX3D, RRP7A, and STUM. Each is linked with RHBG in more than 1 cancer types. Because this analysis shows association rather than direction, both RHBG-to-partner and partner-to-RHBG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MEX3D grouped by RHBG-low versus RHBG-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBG→partner) and Y-score (partner→RHBG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEX3D →	+0.865	+2.831	<.001	.001	3	2
UCEC	RRP7A →	+0.442	+2.724	.003	.003	3	2
UCEC	STUM →	-0.968	-3.700	.001	.001	3	2
UCEC	IGHD2-2 →	+1.178	+1.819	.003	.008	3	2
COAD	ATP13A5-AS1 →	+0.173	+4.602	<.001	<.001	3	2
CESC	BRWD1P3 →	+0.093	+5.010	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 946 associations by consensus.

MEX3D by RHBG expression — UCEC

Explore this box plot interactively →