RHBG

Across TCGA cell cohorts, RHBG RNA expression is significantly associated with the go_rna of many other GO terms, with 2,932 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible RHBG-associated GO terms across cancer lineages are Negative regulation of mRNA metabolic process, Regulation of RNA splicing, and Oxidative phosphorylation. Each is linked with RHBG in more than 8 cancer types. Because this analysis shows association rather than direction, both RHBG-to-partner and partner-to-RHBG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mRNA metabolic process grouped by RHBG-low versus RHBG-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBG→partner) and Y-score (partner→RHBG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of mRNA metabolic process →	+0.073	+0.464	<.001	<.001	3	9
LARGE_INTESTINE	Regulation of RNA splicing →	+0.067	+0.531	<.001	<.001	3	9
OESOPHAGUS	Oxidative phosphorylation →	+0.144	+0.641	<.001	<.001	3	8
LARGE_INTESTINE	Protein stabilization →	+0.062	+0.454	<.001	.001	3	8
OESOPHAGUS	Regulation of protein localization to Cajal body →	+0.090	+0.523	<.001	<.001	3	8
OESOPHAGUS	Positive regulation of protein localization to Cajal body →	+0.090	+0.523	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,932 associations by consensus.

Negative regulation of mRNA metabolic process by RHBG expression — LARGE_INTESTINE

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