RHBG

Across TCGA cell cohorts, RHBG mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RHBG-associated genes across cancer lineages are TP53TG3E, OR13C8, and TNP1. Each is linked with RHBG in more than 1 cancer types. Because this analysis shows association rather than direction, both RHBG-to-partner and partner-to-RHBG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53TG3E grouped by RHBG-low versus RHBG-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBG→partner) and Y-score (partner→RHBG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TP53TG3E →	+0.454	+4.347	<.001	.001	3	1
LUNG_NSCLC_LUAD	OR13C8 →	+0.022	+5.662	<.001	.002	3	1
LARGE_INTESTINE	TNP1 →	+0.128	+4.415	<.001	.007	3	1
LARGE_INTESTINE	OR7A17 →	+0.014	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

TP53TG3E by RHBG expression — SKIN

Explore this box plot interactively →