RHBDL1

Across TCGA pan-cancer cohorts, RHBDL1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated RHBDL1 data layer compared with 26 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher RHBDL1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated RHBDL1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LUAD show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where RHBDL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Quartile	IV	0.067	0.908	.038	10	view →
HNSC	DFS	Median	All	0.903	0.438	.020	6	view →
LUAD	OS	Tertile	II,III,IV	1.000	0.790	.030	3	view →
PDAC	OS	Tertile	III,IV	1.000	0.325	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

RHBDL1–CCRCC (DFS)

Open the CCRCC breakdown →