RHBDF2

Across TCGA patient cohorts, RHBDF2 mutation is significantly associated with the RNA expression of many other genes, with 2,094 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RHBDF2-associated genes across cancer lineages are RPS27L, TRGV11, and TRAJ46. Each is linked with RHBDF2 in more than 2 cancer types. Because this analysis shows association rather than direction, both RHBDF2-to-partner and partner-to-RHBDF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS27L grouped by RHBDF2-low versus RHBDF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RHBDF2→partner) and Y-score (partner→RHBDF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS27L →	+0.661	+3.584	<.001	.002	3	3
SARC	TRGV11 →	+0.183	+5.620	<.001	.004	3	2
SARC	TRAJ46 →	+0.806	+5.224	<.001	.006	3	2
SARC	GTF2IP8 →	+0.095	+5.224	.008	.006	3	2
CESC	MIR4748 →	+0.496	+4.653	<.001	.004	3	2
COAD	FABP7P2 →	+0.191	+4.136	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,094 associations by consensus.

RPS27L by RHBDF2 expression — UCEC

Explore this box plot interactively →