Across TCGA patient cohorts, RGS9BP mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RGS9BP-associated genes across cancer lineages are FOXO3a, JNK_pT183_Y185, and Mre11. Each is linked with RGS9BP in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS9BP-to-partner and partner-to-RGS9BP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS9BP→partner) and Y-score (partner→RGS9BP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a →	-0.128	-3.292	.012	.010	3	1
UCEC	JNK_pT183_Y185 →	-0.191	-2.308	.024	.036	3	1
UCEC	Mre11 →	-0.096	-2.321	.025	.035	3	1
UCEC	Smad4 →	-0.143	-2.321	.018	.035	3	1
UCEC	Caspase-8 →	-0.312	-3.459	.013	.005	3	1
UCEC	Heregulin →	-0.176	-3.169	.004	.019	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

RGS9BP survival (RNA) · tumor vs normal (RNA) · all RGS9BP data types