RGS8

Across TCGA patient cohorts, RGS8 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,028 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RGS8-associated proteins across cancer lineages are CAP2, COPZ2, and FILIP1L. Each is linked with RGS8 in more than 4 cancer types. Because this analysis shows association rather than direction, both RGS8-to-partner and partner-to-RGS8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS8 versus CAP2 in COAD, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS8→partner) and Y-score (partner→RGS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CAP2 →	+0.497	+0.053	<.001	<.001	3	4
OV	COPZ2 →	+0.645	+0.090	.008	.009	2	5
OV	FILIP1L →	+0.478	+0.126	<.001	.003	3	4
PDAC	VIM →	+0.409	+0.092	<.001	<.001	3	4
COAD	CALD1 →	+0.655	+0.050	<.001	<.001	3	3
COAD	COL1A1 →	+0.796	+0.054	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,028 associations by consensus.

RGS8 vs CAP2 — COAD

Explore this scatter interactively →