RGS7

Across TCGA patient cohorts, RGS7 RNA expression is significantly associated with the RNA expression of many other genes, with 14,249 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible RGS7-associated genes across cancer lineages are EFR3B, NBEA, and SORBS2. Each is linked with RGS7 in more than 21 cancer types. Because this analysis shows association rather than direction, both RGS7-to-partner and partner-to-RGS7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS7 versus EFR3B in SCLC, with a Pearson correlation of 0.45.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS7→partner) and Y-score (partner→RGS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	EFR3B →	+1.316	+1.600	<.001	<.001	3	22
SARC	NBEA →	+1.155	+0.832	<.001	<.001	3	22
ACC	SORBS2 →	+1.352	+1.111	<.001	<.001	3	21
SCLC	SGSM1 →	+1.702	+1.587	<.001	<.001	3	21
SCLC	FAM155A →	+2.142	+1.889	<.001	<.001	3	20
SCLC	CACNA2D2 →	+2.077	+1.684	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,249 associations by consensus.

RGS7 vs EFR3B — SCLC

Explore this scatter interactively →