RGS7

Across TCGA patient cohorts, RGS7 protein abundance is significantly associated with the protein abundance of many other proteins, with 13,331 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RGS7-associated proteins across cancer lineages are MGA_S924, NAPEPLD, and ZYG11B. Each is linked with RGS7 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS7-to-partner and partner-to-RGS7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS7 versus MGA_S924 in GBM, with a Pearson correlation of -0.36.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS7→partner) and Y-score (partner→RGS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MGA_S924 →	-0.465	-0.596	<.001	<.001	3	2
GBM	NAPEPLD →	+0.597	+0.874	<.001	<.001	3	2
GBM	ZYG11B →	+0.267	+0.914	<.001	<.001	3	2
BRCA	ATP5ME →	+0.811	+1.945	.002	<.001	3	2
GBM	CPLX1 →	+1.179	+1.068	<.001	<.001	3	2
GBM	RC3H1 →	-0.154	-0.519	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,331 associations by consensus.

RGS7 vs MGA_S924 — GBM

Explore this scatter interactively →