RGS5

Across TCGA patient cohorts, RGS5 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,742 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RGS5-associated proteins across cancer lineages are TNS2, CYGB, and EHD2_S468. Each is linked with RGS5 in more than 8 cancer types. Because this analysis shows association rather than direction, both RGS5-to-partner and partner-to-RGS5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS5 versus TNS2 in CCRCC, with a Pearson correlation of 0.73.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS5→partner) and Y-score (partner→RGS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TNS2 →	+0.514	+1.783	<.001	<.001	3	9
CCRCC	CYGB →	+0.722	+1.731	<.001	<.001	3	9
PDAC	EHD2_S468 →	+0.957	+0.797	<.001	.001	3	9
CCRCC	ERG_S81 →	+0.908	+1.544	<.001	<.001	3	9
UCEC	KANK2 →	+0.657	+0.999	.001	.002	3	9
CCRCC	PPP1R12B →	+0.911	+1.723	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,742 associations by consensus.

RGS5 vs TNS2 — CCRCC

Explore this scatter interactively →