RGS5

Across TCGA patient cohorts, RGS5 protein abundance is significantly associated with the RNA expression of many other genes, with 337 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible RGS5-associated genes across cancer lineages are MICALL1, AP1B1, and EFS. Each is linked with RGS5 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS5-to-partner and partner-to-RGS5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS5 versus MICALL1 in CCRCC, with a Pearson correlation of -0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS5→partner) and Y-score (partner→RGS5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MICALL1 →	-0.386	-0.417	.002	.002	3	1
CCRCC	AP1B1 →	-0.464	-0.454	<.001	<.001	3	1
CCRCC	EFS →	-1.058	-0.402	.001	.003	3	1
CCRCC	FGD1 →	-0.561	-0.399	<.001	.004	3	1
CCRCC	WFDC1 →	-1.196	-0.625	.004	.007	3	1
CCRCC	CSK →	-0.390	-0.461	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 337 associations by consensus.

RGS5 vs MICALL1 — CCRCC

Explore this scatter interactively →