RGS4

Across TCGA patient cohorts, RGS4 protein abundance is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. OV shows the largest number of these associations.

The most reproducible RGS4-associated genes across cancer lineages are MAK16, ACY3, and GSTM3. Each is linked with RGS4 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS4-to-partner and partner-to-RGS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS4 versus MAK16 in OV, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS4→partner) and Y-score (partner→RGS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MAK16 →	+0.896	+1.866	.007	.005	3	1
OV	ACY3 →	-1.770	-1.866	<.001	.005	2	1
OV	GSTM3 →	+1.256	+1.866	.008	.005	2	1
OV	ANP32E →	+0.950	+1.866	.003	.005	2	1
OV	CNIH4 →	+0.536	+1.866	.009	.005	2	1
OV	STK4-AS1 →	+0.686	+1.866	.008	.005	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

RGS4 vs MAK16 — OV

Explore this scatter interactively →