RGS3

Across TCGA patient cohorts, RGS3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,146 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RGS3-associated proteins across cancer lineages are ZYX, RCN3, and YARS2. Each is linked with RGS3 in more than 5 cancer types. Because this analysis shows association rather than direction, both RGS3-to-partner and partner-to-RGS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS3 versus ZYX in COAD, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS3→partner) and Y-score (partner→RGS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ZYX →	+0.406	+0.561	<.001	<.001	3	6
GBM	RCN3 →	+0.755	+0.492	<.001	.002	3	6
OV	YARS2 →	-0.415	-0.592	.002	.002	3	6
LSCC	TNS2_S120 →	+0.371	+0.284	.001	.001	3	5
OV	PRKG1 →	+0.731	+0.603	<.001	<.001	2	6
CCRCC	TGFB1I1 →	+0.556	+0.528	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,146 associations by consensus.

RGS3 vs ZYX — COAD

Explore this scatter interactively →