RGS3

Across TCGA patient cohorts, RGS3 protein abundance is significantly associated with the protein abundance of many other proteins, with 20,279 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RGS3-associated proteins across cancer lineages are RGS3_S943, RGS3_S1007, and RGS3_S917. Each is linked with RGS3 in more than 7 cancer types. Because this analysis shows association rather than direction, both RGS3-to-partner and partner-to-RGS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RGS3 versus RGS3_S943 in OV, with a Pearson correlation of 0.42.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS3→partner) and Y-score (partner→RGS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RGS3_S943 →	+0.793	+0.785	<.001	<.001	3	8
LSCC	RGS3_S1007 →	+0.605	+0.297	<.001	<.001	3	8
CCRCC	RGS3_S917 →	+0.476	+0.431	.001	.001	3	7
LSCC	RGS3_S1044 →	+0.504	+0.292	<.001	<.001	3	6
LSCC	CORO1A →	+0.573	+0.415	<.001	<.001	3	6
GBM	DOCK8 →	+0.513	+0.412	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,279 associations by consensus.

RGS3 vs RGS3_S943 — OV

Explore this scatter interactively →