RGS3

Across TCGA cell cohorts, RGS3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,383 significant associations in total. CNS shows the largest number of these associations.

The most reproducible RGS3-associated GO terms across cancer lineages are Positive regulation of mononuclear cell migration, PML body organization, and Regulation of fibroblast proliferation. Each is linked with RGS3 in more than 9 cancer types. Because this analysis shows association rather than direction, both RGS3-to-partner and partner-to-RGS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mononuclear cell migration grouped by RGS3-low versus RGS3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS3→partner) and Y-score (partner→RGS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of mononuclear cell migration →	+0.152	+2.434	<.001	<.001	3	10
BONE	PML body organization →	+0.201	+2.574	<.001	<.001	3	10
SOFT_TISSUE	Regulation of fibroblast proliferation →	+0.063	+1.564	.001	<.001	2	10
BONE	Positive regulation of cell-substrate junction organization →	+0.138	+1.685	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Intracellular receptor signaling pathway →	+0.056	+1.176	<.001	<.001	3	9
BONE	Neuropilin signaling pathway →	+0.245	+2.797	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,383 associations by consensus.

Positive regulation of mononuclear cell migration by RGS3 expression — BONE

Explore this box plot interactively →