RGS21

Across TCGA patient cohorts, RGS21 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible RGS21-associated genes across cancer lineages are Osteoblast and Preadipocytes. Each is linked with RGS21 in more than 1 cancer types. Because this analysis shows association rather than direction, both RGS21-to-partner and partner-to-RGS21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Osteoblast grouped by RGS21-low versus RGS21-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS21→partner) and Y-score (partner→RGS21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	Osteoblast →	+0.023	+4.035	.049	.012	3	2
COAD	Preadipocytes →	+0.032	+4.754	.044	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Osteoblast by RGS21 expression — HNSC

Explore this box plot interactively →