RGS21

Across TCGA cell cohorts, RGS21 RNA expression is significantly associated with the go_rna of many other GO terms, with 333 significant associations in total. BONE shows the largest number of these associations.

The most reproducible RGS21-associated GO terms across cancer lineages are Glycosphingolipid catabolic process, Antigen processing and presentation of exogenous antigen, and Natural killer cell chemotaxis. Each is linked with RGS21 in more than 2 cancer types. Because this analysis shows association rather than direction, both RGS21-to-partner and partner-to-RGS21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Glycosphingolipid catabolic process grouped by RGS21-low versus RGS21-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGS21→partner) and Y-score (partner→RGS21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Glycosphingolipid catabolic process →	-0.113	-0.043	.002	.005	3	3
BONE	Antigen processing and presentation of exogenous antigen →	-0.181	-0.101	<.001	.002	3	3
BONE	Natural killer cell chemotaxis →	-0.701	-0.161	.002	.007	3	3
SOFT_TISSUE	Regulation of systemic arterial blood pressure by hormone →	-0.188	-0.038	.001	.008	3	2
BONE	Ribosome hibernation →	-0.125	-0.150	.004	.004	3	2
BONE	Mesodermal cell fate commitment →	-0.955	-0.169	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 333 associations by consensus.

Glycosphingolipid catabolic process by RGS21 expression — SOFT_TISSUE

Explore this box plot interactively →